by Bioinfocodes Bioinforange | Jul 10, 2026 | Bioinfonews
Plague is recognized as one of the most devastating infectious diseases in human history. However, the extent to which the early evolutionary forms of the bacterium Yersinia pestis, the causative agent of plague, were lethal has long been a subject of debate. Since...
by Bioinfocodes Bioinforange | Jun 30, 2026 | Bioinfonews
Foundation models (FMs) are artificial intelligence models trained on large-scale datasets and possessing generalized learning capabilities that can be used in various tasks. Decoding DNA syntax provides an indispensable infrastructure for processes such as disease...
by Bioinfocodes Bioinforange | Jun 23, 2026 | Bioinfonews
Translation is one of the most fundamental biological processes essential for the continuation of life, and viruses depend on the host cell’s translational machinery for replication. However, a significant genetic mismatch exists between giant viruses such as...
by Bioinfocodes Bioinforange | Jun 16, 2026 | Bioinfonews
Under normal circumstances, the mammalian genome is protected within the safe boundaries of the interphase nucleus, and the stability of cellular functions is maintained by this spatial separation. However, genomic instability caused by factors such as cell division...
by Bioinfocodes Bioinforange | Jun 9, 2026 | Bioinfonews
Viruses rank among the most abundant biological entities in the biosphere and display remarkable genetic diversity. Their ability to infect bacteria, archaea, and eukaryotes has established viral systems as a significant area of biological research. Despite this, the...
by Bioinfocodes Bioinforange | Jun 2, 2026 | Bioinfonews
Proteins, as the fundamental functional units of cellular life, govern a wide range of biochemical processes, from metabolism to intracellular signaling. Advances in high-throughput sequencing technologies have led to the accumulation of over 250 million protein...
by Bioinfocodes Bioinforange | May 26, 2026 | Bioinfonews, Bioinformatics
Chemical experiments conducted in laboratories have become faster and more reproducible with the advancement of automation and robotic systems. Although self-driving laboratory (SDL) systems, in particular, have the potential to accelerate experimental processes, they...
by Bioinfocodes Bioinforange | May 19, 2026 | Bioinfonews
Multiple myeloma is a malignancy characterized by the uncontrolled proliferation of plasma cells in the bone marrow and accounts for approximately 10% of all hematological cancers. Despite advances in treatment modalities such as proteasome inhibitors,...
by Bioinfocodes Bioinforange | May 15, 2026 | Bioinfonews, Bioinformatics
Protein allostery (the phenomenon in which a signal received by one region of a protein triggers a response in a distant functional region) constitutes the fundamental mechanism of real-time information processing and energy transfer at the cellular level. The vast...
by Bioinfocodes Bioinforange | May 5, 2026 | Bioinfonews
The three-dimensional structure of RNA (ribonucleic acid) molecules is of fundamentally important for cellular processes. Many biological functions, including ribosome formation (the cell’s protein factory), depend on the correct folding of RNA. However, RNA molecules...
by Bioinfocodes Bioinforange | Apr 28, 2026 | Bioinfonews
The integration of artificial intelligence systems into scientific research processes has become a subject of growing interest in the life sciences in recent years. Research workflows in fields such as biology, drug discovery, and translational medicine involve...
by Fatma Duran | Apr 23, 2026 | Bioinfonews
Recent advancements in the field of molecular biology and biophysics have increased the importance of Artificial Intelligence (AI)-based approaches in order to deciphering evolutionary background of protein evolution. In order to complete their cellular tasks,...
by Fatma Duran | Apr 21, 2026 | Bioinfonews
Inflammatory bowel disease (IBD) is a group of chronic and recurrent gastrointestinal disorders encompassing ulcerative colitis and Crohn’s disease, with a prevalence ranging from 6–8 million cases worldwide. Current clinical treatments (5-aminosalicylic acid,...
by Fatma Duran | Apr 16, 2026 | Bioinfonews
Overcoming the Gram-Negative Barrier: Intracellular Drug Tracking with CHAMPGram-negative bacterial pathogens represent a formidable challenge in modern drug development due to their complex outer membrane structures, which act as a selective barrier preventing the...
by Bioinfocodes Bioinforange | Apr 9, 2026 | Bioinfonews
The postpartum period undergoes significant neuroanatomical remodeling in maternal brain structure, which exerts profound effects on both parenting behaviors and child development. However, research regarding the specific risk factors influencing maternal mental...
by Bioinfocodes | Mar 13, 2026 | Bioinfonews
Functional processes in the human brain are shaped through complex interactions and correlations (relational links) between different brain regions. In neuroscience, the role of large-scale neural activities and inter-regional functional networks in cognitive...
by Bioinfocodes | Feb 2, 2026 | Bioinfonews
In cases of septic shock arising from severe Acute Respiratory Distress Syndrome (ARDS) accompanied by necrotizing pneumonia (pneumonia characterized by the death of lung tissue), mortality rates can exceed 80%. Within this clinical context, lung transplantation is...
by Bioinfocodes | Jan 31, 2026 | Bioinfonews
Interpreting the biological effects of genetic variation is regarded as one of the fundamental challenges of modern biology. More than 98% of the variations in the human genome reside within protein non-coding regions, and these variants can influence gene expression,...
by Bioinfocodes | Dec 25, 2025 | Bioinfonews
Reliable analysis of biological data obtained through microscopy is largely dependent on accurate cell segmentation. Thanks to new-generation deep learning (DL) technologies, two-dimensional (2D) cell segmentation offers generalised solutions across various cell types...
by Bioinfocodes | Dec 23, 2025 | Bioinfonews
Artificial intelligence (AI), and particularly deep learning (DL), holds transformative potential for the biological sciences, spanning applications from genetic engineering to disease diagnosis and therapeutic development. DL models trained on DNA sequences can...
