Unveiling the Microbial Frontier: Exploring CRISPR’s Hidden Biochemical Gems
The exponential growth of protein sequence databases challenges existing mining methods, hindering the discovery of rare families and functional systems, particularly within diverse CRISPR-Cas systems. Systematic sequencing approaches have proven powerful in...
CRISPR/Cas9 Based Gene Therapy
Ece OdabaşıT., Gülnur UzunE. The gene, which is the basic unit of heredity in living things, structurally contains the untranslated region (UTR), enhancer or silencer, and promoter areas at the 5' and 3' ends, and coding exons and non-coding introns between them. Gene...
Hunger Decoded: Brain’s Appetite Control Symphony
Feeding behavior is a complex process that is regulated by a variety of factors, including hormones, neurotransmitters, and environmental cues. Recent research has identified two key players in the regulation of feeding behavior: Prolactin-releasing hormone (PRLH) and...
The Dark Side of Artificial Intelligence: Formation of Fake Dataset with GPT-4
Since its introduction in 2022, ChatGPT has proven to be advantageous in furnishing users with access to information through systematic updates. Presently, aiming for enhanced efficiency, GPT-4, a sophisticated Large Language Model (LLM) created by ChatGPT, has been...
YAP: The Cipher of Fate and Proliferation
Cellular decision-making mechanisms are crucial for the proper development of an organism. However, the process by which cells process and transmit incoming information is not fully understood, making it an intriguing subject. Transcription factors, whose effects on...
Synthetic Biology: Extraordinarily Advanced Systems
Zehra Nur KoyuncuT., Nida Dereli ÇalışkanE. With the advancement of technology, there has been a tremendous expansion of scientific knowledge. This flow of information has led to the emergence of interdisciplinary fields such as "Synthetic Biology (SB)”. This...
Anthrobots: Biobots Created without Genetic Manipulation
In recent years, the advancement of biobot technology has ushered in unprecedented opportunities for the execution of multifarious tasks within and around living organisms. Biobots, intricate microscopic robotic systems, represent synthetic biological structures...
Life, Space, and Future: Astroecology
Esma TopaloğluT., Gülnur UzunE. A multidisciplinary approach has become the main feature of scientific research that points to benefit from the diversity of information of complex systems on or outside of Earth, like biodiversity, ecological systems, and galaxies1....
RNA-based Therapeutics and The Future of RNA Therapy
Dilan AğırbaşA., Ebru KavaklıE. RNA therapy is a type of treatment that regulates biological pathways with RNA molecules to remedy a particular disease1. Manipulating gene expression and producing therapeutic proteins are fundamental functions of RNA therapies....
Stem Cell Technologies: Regenerative Medicine and Clinical Applications
Eslem EkemenT., Nida Dereli ÇalışkanE., Ebru KavaklıR. Stem cells are a group of cells that have the properties of differentiation, proliferation, and continuous self-renewal and can enable the production, repair, and regeneration of many tissues1-3. At the same time,...